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Supplements are a science. Ours especially.

Every Land Lab formula is born in the lab, shaped by clinical evidence, and informed by the world's oldest living culture. From cellular action to systemic impact, we test every claim.

Our approach

At Land Lab, we approach product development through the lens of translational science — integrating Indigenous ecological knowledge with modern nutritional biochemistry, toxicology, and clinical research. Our goal is clear: to develop evidence-based, functional food formulations that are safe, bioactive, and effective.

This work is guided by our Scientific Advisory Council — a multidisciplinary team of biochemists, doctors, dietitians, and naturopaths. Together, they ensure that every decision is informed by evidence, clinical rationale, and a deep respect for the native and non-native ingredients we work with.

Why native plants?

Australian native plants have evolved under some of the harshest environmental conditions on the planet. In response to chronic stressors like UV exposure, drought, and nutrient-poor soils, many of these plants have developed unique biochemical defence systems — including unusually high levels of polyphenols, antioxidants, prebiotic fibres, and secondary metabolites. These aren’t just botanical adaptations — they’re potential mechanisms of action in human physiology.

Yet despite millennia of use by First Nations communities, many of these botanicals remain under-researched in the context of human health. There is limited clinical or mechanistic data to support their therapeutic use. We believe this is a missed opportunity — both for science and for health.

Our Scientific Process

Before we consider using a native ingredient, we undertake a multi-phase research pipeline:

Literature review & traditional use analysis

We begin with a dual review of existing peer-reviewed evidence and the documented traditional uses of each plant. This includes known bioactives, safety profiles, pharmacokinetics (where available), and ethnobotanical context. Consultation with Indigenous partners ensures cultural relevance and helps inform appropriate use.

In Vitro safety & mechanistic studies

All native ingredients undergo toxicological and antinutrient screening using co-cultured intestinal cell lines. We assess:

  • Cytotoxicity
  • Antinutrient content (e.g. phytates, oxalates, lectins, tannins)
  • Presence of potentially harmful alkaloids or secondary compounds

Gut health & functional analysis

We use an advanced in vitro simulated gut model to examine how ingredients and final formulations affect:

  • Microbial diversity and composition
  • Short-chain fatty acid (SCFA) production
  • Antioxidant activity
  • Phenolic metabolite generation
  • Prebiotic effects

This level of testing provides insight not just into what’s in the plant, but what it does once metabolised — including colonic fermentation pathways and postbiotic activity.

Formulation & delivery science

We collaborate with manufacturers to develop delivery systems (e.g. microencapsulation) that preserve bioactivity through the digestive tract. Final formulations are then re-tested in gut models to validate compound stability, release kinetics, and functional activity.

Clinical validation beyond the bench

We’re in the process of designing observational studies and randomised controlled trials (RCTs) to assess the health impacts of our formulations in humans. This includes gut health endpoints (such as microbiota changes and symptom scores), as well as secondary outcomes related to inflammation, micronutrient absorption, and quality of life.

Respect for knowledge systems

Our research does not supersede traditional knowledge — it integrates with it. We see traditional use as a form of longitudinal human data, passed down over generations. Traditional knowledge offers deep, long-term insights into how plants have been used safely and effectively. We honour that by consulting with First Nations partners at every stage, by co-designing fair economic partnerships with our First Nations partners, and by ensuring that any scientific research we conduct is additive, not extractive. Scientific validation doesn’t replace Indigenous knowledge; it expands the evidence base to ensure safety, efficacy, and appropriate modern use.

We aim to contribute meaningfully to the body of scientific literature on Australian native plants, while safeguarding the cultural and intellectual property of the First Nations communities who have long stewarded them.

Meet Our Science Advisory Board

Our Scientific Board consists of scientists, researchers, doctors, and health professionals, including First Nations leaders. Each member brings deep domain expertise across fields like maternal health, biochemistry, pharmacognosy, and nutritional science, ensuring that every decision is grounded in evidence, not opinion. This diverse group ensures our products are evidence-based, culturally respectful, and therapeutically relevant.

Dr. Hannah LaBrooy

MD, MPH

Felicity Kerslake

Bush Naturopath and Nutritionist

Dr. Luke Williams

PhD

Dr. Oladipupo Adiamo

PhD

Chelsea McCallum

Accredited Practising Dietitian

Nikki Preiner

Accredited Practising Dietitian

Lauren Jeffery

Registered Pharmacist

In partnership with the University of Queensland

We’ve partnered with research institutions like the University of Queensland, one of Australia’s most respected research institutions, to take a deeper look into how our formulas behave in the body.

They conduct nutritional analyses as well as in vitro studies using tools such as the simulated gut model, which simulates the different compartments of the human gastrointestinal tract — including the stomach, small intestine, and colon — and is used to study digestion, microbial metabolism, and the effects of different compounds on the gut microbiome.

Through advanced studies, including simulated gut models and in vitro testing, we test for:
• Nutrient absorption (bioavailability)
• Microbial activity and gut health impact
• Comparative effects between native and non-native ingredients

This isn’t just product development, it’s evidence-led formulation.

Transform Your Health with Our Science.

Shop our range of evidence-based supplements powered by native Australian plants.

Mother Dose™ Prenatal Multivitamin

Mother Dose™ Prenatal Multivitamin

SHOP NOW

Dive Deeper

Explore the Science Behind Mother Dose™

Want to know what makes our first formula different? Explore the evidence, thinking, and formulation decisions behind Mother Dose™—our flagship prenatal, and the first of many products to come.

For Curious Minds:
Download our peer-reviewed White Paper for a full breakdown of clinical rationale, ingredient selection, and supporting research.

For Practitioners:
Access our Health Professional Fact Sheet for a quick-reference overview of key ingredients, dosages, and clinical indications.

Third-party tested, every time

Every Land Lab formula undergoes strict third-party testing to confirm:
• Nutrient levels match the label
• No heavy metals or contaminants
• Microbial safety standards are met

REVIEWED BY OVER 50 HEALTHCARE EXPERTS

Our flagship prenatal, Mother Dose™, has been peer-reviewed by doctors, dietitians, naturopaths and midwives.

SEE ALL REVIEWS

"This product has been so thoughtfully crafted to nourish the body with nutrients that are easily absorbed. The addition of traditional indigenous ingredients and consideration of addressing morning sickness really highlights how much care was taken to nurture women’s bodies through conception and pregnancy."

Alex Thomson, Registered Midwife

"Land Lab’s prenatal supplement is a fantastic choice; it’s high-quality, evidence-based, and formulated with the highest choline dosage on the market."

Freya Lawler, Naturopath

TRANSFORM YOUR HEALTH WITH OuR SCIENCE